Lesch Nyhan Syndrome

Lesch Nyhan Syndrome Lesch Nyhan Syndrome Lesch Nyhan Syndrome (LNS) was first reported in 1964 by Michael Lesch and William L. Nyhan. It is a uncommon disorder located on the x chromosome. It is a sex-linked trait, which means that it is passed from mother to son. This condition can be restore or occur spontaneously as a offshoot of a genetic mutation. It usually appears once in both 100,000 male births. Since the defective gene is recessive, females almost never wrap symptoms of the disease. However, they can be carriers of the allele.

Lesch Nyhan is associated with an almo st complete absence of the enzyme HGPRTase (hypoxanthene tempo phosphoribosil transferase). This is the enzyme that recycles hypoxanthen and gibibyte, which are two of the genetic building blocks. When this enzyme is not present, the hypoxanthen and gigabyte are converted into excessive uric acid. Children around quaternion to six months old are usually diagnosed with LND when orange, sand l...If you handle to get a full essay, order it on our website: BestEssayCheap.com

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